Emory

Research Specialist, Lead

Job Number
77760
Job Type
Regular Full-Time
Division
School Of Medicine
Department
SOM: Peds: Cystic Fibrosis
This position may involve the following Health and Safety issues:
Working with animals.
Job Category
Laboratory
Location : Name
Emory Campus-Clifton Corridor
Campus Location (For Posting) : Location
US-GA-Atlanta

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Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the diversity and excellence of our academic community.

Description

The Center for Cystic Fibrosis and Airways Disease Research (CF-AIR), a joint entity within Emory University and Children’s Healthcare of Atlanta, is currently seeking a Lead Research Specialist to join the laboratory of Dr. Kathryn Oliver to broadly investigate ways in which ribosome velocity and mRNA surveillance impact aberrant protein synthesis in the context of cystic fibrosis (CF) and other inherited conditions.

 

JOB DESCRIPTION:

  • Under minimal supervision, performs a variety of specialized and complex research and laboratory tests and procedures.
  • Uses independent judgment in applying or adapting scientific techniques.
  • May assist in protocol design.
  • Investigates and proposes alternative experimental procedures for consideration by a principal investigator.
  • Assists in planning and scheduling research procedures.
  • Analyzes and interprets results of studies.
  • Demonstrates and trains others in the proper use/operation of laboratory techniques and equipment.
  • Calibrates, troubleshoots and performs routine repair and maintenance of equipment.
  • Reviews literature for related research developments and techniques and compiles findings.
  • Monitors laboratory processes to maintain quality assurance standards.
  • Records results of studies, compiles and analyzes data and prepares charts and graphs.
  • Monitors the handling, storage and disposal of hazardous substances.
  • Performs related responsibilities as required.
  • Employees in this classification may be required to work with, take specific precautions against and/or be immunized against potentially hazardous agents.

ADDITIONAL JOB DETAILS:

  • Processes clinical specimens (e.g. respiratory epithelia, blood) from CF and non-CF donors, as well as a variety of tissues from C57BL/6 mice.
  • Performs light/fluorescent microscopy, cell culture, drug delivery, and nucleotide transfection.
  • Conducts molecular biology techniques such as DNA/RNA isolation and purification; PCR amplification; qRT-PCR; gel electrophoresis; and preparation of sequencing libraries.
  • Executes biochemical protocols including but not limited to cell viability assays; protein quantification and visualization (e.g. western blot, protein half-life, immunoprecipitation); cell surface biotinylation; mRNA stability assays; sucrose gradient fractionation; ribosome run-off assays; and electrophysiology (e.g. short-circuit current analyses).
  • Concerning experiments described above, contributes to design, planning, and data analysis using Microsoft products, GraphPad Prism, R, and/or other software as applicable.
  • Contributes to grants, presentations, and/or manuscript publications as appropriate.
  • Liaises with other laboratories as needed.
  • Embrace working with individuals from diverse backgrounds (e.g. gender, race/ethnicity, LGBTQ+, physical ability, socioeconomic status, etc.).
  • Ability to conduct themselves with integrity and professionalism.
  • The ideal candidate should be a motivated, detail-oriented, dependable self-starter with a positive attitude and passion for research.
  • Excellent interpersonal, written, and verbal communication skills.
  • The Lead Research Specialist will be a team player who is willing to learn on the job and collaborate with other members of the laboratory and department/center.
  • Strong analytical and problem-solving skills.
  • Demonstrated proficiency with Microsoft Office and Office 365 applications.
  • Ability to work independently and in a fast-faced environment.
  • Studies will address feasibility of ribosomal suppression as a novel therapeutic strategy for overcoming refractory defects in the CF transmembrane conductance regulator (CFTR) – with particular emphasis on premature termination codons.
  • This includes mechanistic evaluation of global and transcript-specific effects on ribosome fidelity and speed, in addition to biochemical assessments of protein biogenesis and activity.
  • Research projects are highly innovative and translational, incorporating use of primary human airway epithelia and animal tissues.
  • The position reports directly to Dr. Kathryn Oliver, Assistant Professor in the Division of Pulmonary, Allergy/Immunology, Cystic Fibrosis, and Sleep within the Department of Pediatrics in the Emory University School of Medicine. To learn more about Dr. Oliver’s background and research, please visit:
    https://www.pedsresearch.org/people/faculty/kathryn-oliver-phd
  • The new hire will work to ensure the highest levels of responsible conduct in research and quality laboratory support, in addition to strong communication with Dr. Oliver, co-workers, administrative staff, department/center leadership, and other research support services.

MINIMUM QUALIFICATIONS:

  • Bachelor's degree in a scientific field and two years of research experience, or equivalent combination of experience, education, and training.

NOTE: Position tasks are required to be performed in-person at an Emory University location; working remote is not an option. Emory reserves the right to change this status with notice to employee.

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Emory University is dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, gender, genetic information, age, disability, sexual orientation, gender identity, gender expression, and veteran's status. Emory University does not discriminate in admissions, educational programs, or employment on the basis of any factor stated above or prohibited under applicable law. Students, faculty, and staff are assured of participation in University programs and in the use of facilities without such discrimination. Emory University complies with Executive Order 11246, as amended, Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veteran's Readjustment Assistance Act, and applicable executive orders, federal and state regulations regarding nondiscrimination, equal opportunity and affirmative action. Emory University is committed to achieving a diverse workforce through application of its affirmative action, equal opportunity and nondiscrimination policy in all aspects of employment including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training. Inquiries regarding this policy should be directed to the Emory University Department of Equity and Inclusion, 201 Dowman Drive, Administration Building, Atlanta, GA 30322.

 

Emory University is committed to providing reasonable accommodations to qualified individuals with disabilities upon request. To request this document in an alternate format or to request a reasonable accommodation, please contact the Department of Accessibility Services at 404-727-9877 (V) | 404-712-2049 (TDD). Please note that one week advance notice is preferred.

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